| | Runs | playerId | seasonId | clubId | matchId | Runs | Player | Team | Season | Grade | Round | Inns | Opponent |
| 1 | 110 | 573498 | 153 | 4698 | 3565175 | 110 | Tahlia Wilson | St George-Sutherland | 2020/2021 | First Grade | 13 | 1 | Universities |
| 2 | 108 | 977676 | 153 | 4698 | 3568159 | 108* | Lucy Finn | St George-Sutherland | 2020/2021 | U18 Brewer Shield | 17 | 1 | Parramatta |
| 3 | 104 | 1117885 | 153 | 4698 | 3568147 | 104* | Karina Bell | St George-Sutherland | 2020/2021 | U18 Brewer Shield | 14 | 1 | Bankstown |
| 4 | 104 | 705141 | 153 | 4698 | 3565311 | 104* | Rhiannon Dick | St George-Sutherland | 2020/2021 | First Grade | 18 | 1 | Bankstown |
| 5 | 95 | 630692 | 153 | 4698 | 3565311 | 95 | Cailyn Fountain | St George-Sutherland | 2020/2021 | First Grade | 18 | 1 | Bankstown |
| 6 | 79 | 772491 | 153 | 4698 | 3565140 | 79 | Joanne Kelly | St George-Sutherland | 2020/2021 | First Grade | 6 | 1 | Gordon |
| 7 | 74 | 772491 | 153 | 4698 | 3565135 | 74* | Joanne Kelly | St George-Sutherland | 2020/2021 | First Grade | 5 | 1 | Penrith |
| 8 | 73 | 977676 | 153 | 4698 | 3568156 | 73 | Lucy Finn | St George-Sutherland | 2020/2021 | U18 Brewer Shield | 16 | 1 | Gordon |
| 9 | 71 | 630692 | 153 | 4698 | 3565308 | 71 | Cailyn Fountain | St George-Sutherland | 2020/2021 | First Grade | 17 | 1 | Sydney |
| 10 | 68 | 705141 | 153 | 4698 | 3565191 | 68 | Rhiannon Dick | St George-Sutherland | 2020/2021 | First Grade | 16 | 1 | Gordon |
| 11 | 64 | 977676 | 153 | 4698 | 3565659 | 64* | Lucy Finn | St George-Sutherland | 2020/2021 | Second Grade | 6 | 1 | Gordon |
| 12 | 62 | 1425197 | 153 | 4698 | 3567639 | 62 | Makayla Alexander | St George-Sutherland | 2020/2021 | U18 Brewer Shield | 4 | 1 | Bankstown |
| 13 | 60 | 977676 | 153 | 4698 | 3567979 | 60* | Lucy Finn | St George-Sutherland | 2020/2021 | U18 Brewer Shield | 9 | 1 | Campbelltown-Camden |
| 14 | 58 | 1376331 | 153 | 4698 | 3568156 | 58 | Caitlin Schofield | St George-Sutherland | 2020/2021 | U18 Brewer Shield | 16 | 1 | Gordon |
| 15 | 58 | 772491 | 153 | 4698 | 3565308 | 58* | Joanne Kelly | St George-Sutherland | 2020/2021 | First Grade | 17 | 1 | Sydney |
| 16 | 57 | 772491 | 153 | 4698 | 3565154 | 57* | Joanne Kelly | St George-Sutherland | 2020/2021 | First Grade | 9 | 1 | Campbelltown-Camden |
| 17 | 56 | 977676 | 153 | 4698 | 3565654 | 56 | Lucy Finn | St George-Sutherland | 2020/2021 | Second Grade | 5 | 1 | Penrith |
| 18 | 55 | 630692 | 153 | 4698 | 3565191 | 55 | Cailyn Fountain | St George-Sutherland | 2020/2021 | First Grade | 16 | 1 | Gordon |
| 19 | 54 | 772491 | 153 | 4698 | 3565186 | 54 | Joanne Kelly | St George-Sutherland | 2020/2021 | First Grade | 15 | 1 | Penrith |
| 20 | 53 | 1108268 | 153 | 4698 | 3567621 | 53* | Stephanie O'Sullivan | St George-Sutherland | 2020/2021 | U18 Brewer Shield | 1 | 1 | Campbelltown-Camden |
| 21 | 52 | 93666 | 153 | 4698 | 3565672 | 52 | Stephanie Gillett | St George-Sutherland | 2020/2021 | Second Grade | 9 | 1 | Campbelltown-Camden |
| 22 | 50 | 977676 | 153 | 4698 | 3567626 | 50* | Lucy Finn | St George-Sutherland | 2020/2021 | U18 Brewer Shield | 2 | 1 | Northern District |
Note: Qualification levels for this report are 50 and 100 runs.
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